Belfry Therapeutics collaborates with the University of Nottingham in the development of quorum sensing inhibitors

UK-based bio-pharmaceutical company Belfry Therapeutics Ltd announced today that it will be collaborating with two leading researchers, Professor Miguel Cámara (Co-director of the National Biofilm Innovations Centre) and Dr Michael Stocks, who are based at the Centre of Biomolecular Sciences (CBS), University of Nottingham, under the MRC Proximity to Discovery: Industry Engagement Fund. The preliminary research will be focused on assessing the Company’s Antibiotic-Assisted Translocation Platform (AATPTM) technology with novel inhibitors of the Pseudomonas aeruginosa quorum sensing regulator PqsR that have been developed by the CBS and which could be key to treating infections caused by this organism through attenuating virulence and sensitising biofilms to the action of existing antibiotics.
Dr Martin Quibell, co-founder and CSO, said: “The MRC Proximity to Discovery: Industry Engagement Fund aims to foster early collaborations and knowledge exchange between industry and academic researchers in the area of therapeutic innovation. We look forward to collaborating with Miguel and Michael in their preliminary work in developing an innovative approach to treat infections caused by Pseudomonas aeruginosa”.

About Belfry Therapeutics Ltd
Belfry Therapeutics Ltd is an Oxford-based biopharmaceutical company founded in 2016 that aims to transform the treatment of infections caused by multi-drug resistant Gram-negative pathogens. The executive team is led by Fraser Murray (Chief Executive Officer), Martin Quibell (Chief Scientific Officer) and Timothy Schulz-Utermoehl (Chief Operating Officer). Other co-founders are Timothy Luker and Stuart Onions. www.belfrytherapeutics.com

About The Centre for Biomolecular Sciences, University of Nottingham
The Centre for Biomolecular Sciences (CBS) is home to over 300 scientists.  It’s dedicated to interdisciplinary and fundamental scientific research. £40 million has been invested in chemistry and biology labs, giving us the tools to make remarkable advances. The CBS is a centre of scientific excellence hosting research groups from the Schools of Chemistry, Medicine, Life Sciences and Pharmacy. For further information visit https://www.nottingham.ac.uk/cbs/.

The National Biofilms Innovation Centre
The National Biofilms Innovation Centre is an Innovation Knowledge Centre (IKC) jointly funded by the BBSRC, Innovate UK, and the Hartree Centre. NBIC’s mission is to establish a network of research and innovation capacity catalysing collaboration with industry in the study of biofilms to achieve breakthrough innovation .  Further information can be obtained at https://biofilms.ac.uk.