University of Leeds – Partner University

For inquiries, please contact Professor Chris Carr (c.carr@leeds.ac.uk) and Professor Deidre Devine (D.A.Devine@leeds.ac.uk).

Faculty of Medicine & Health
School of Dentistry

Research areas and focus

  1. Developing laboratory models of oral biofilms
  2. Composition and functional activity of oral biofilms in health & disease
  3. Identifying factors that drive dysbiosis
  4. Impact of antimicrobial agents
  5. Atomic force microscopy of model biofilm formation, bacterial cell surface structure and cell-cell adhesion.
  6. Pre- and probiotics
  7. Computer modelling of biofilms
  8. Photodynamic therapy
  9. Developing antimicrobial materials (dental, tissue engineering, biomineralisation, wounds)
  10. Clinical studies and trials related to biofilm infections, devices etc

Facilities

  • Anaerobic microbiology
  • Constant depth film fermenter
  • Chemostat
  • Confocal, scannning electron microscopy
  • Atomic Force Microscopy facility
  • Micro- and nano-CT
  • Cell culture laboratories
  • Biomaterials and Bioengineering lab facilities – to add details
  • Biochemistry and molecular biology laboratory – to add details
  • Leeds Dental Translational and Clinical Research Unit (DenTCRU): http://medhealth.leeds.ac.uk/info/471/dental_translational_and_clinical_research_unit
  • Skeletal tissue Bank
  • University of Leeds Next Generation Sequencing facility

Researchers

Professor Deirdre Devine
Dr Thuy Do
Professor Philip Marsh
Dr Josie Meade
Professor David Wood
Dr Simon Wood
Dr Neil Thomson
Dr Jing Kang
Professor Susan Pavitt
Dr David Head

Faculty of Medicine & Health
School of Medicine, Leeds Institute of Biomedical and Clinical Sciences
Healthcare Associated Infections Research Group

Research areas and focus

  1. Clostridium difficile biofilm formation, molecular interactions and role in recurrent Clostridium difficile infection (CDI).
  2. Biofilm formation by the intestinal microbiota, synergistic and antagonistic interactions, molecular interactions, multispecies biofilms.
  3. Effects of antimicrobial agents on biofilm formation, dispersal, antimicrobial tolerance and resistance.

Facilities

Researchers

Professor Mark Wilcox

Dr Caroline Chilton

Dr Anthony Buckley

Faculty of Medicine & Health
School of Healthcare

Research areas and focus

  1. Wound infections

Researchers

Andrea Nelson
Angela Oates

Faculty of Biological Sciences
School of Molecular & Cellular Biology

Research areas and focus

  1. Antibiotic resistance
  2. Development of new drugs

Researchers

Alex O’Neill

Faculty of Mathematical and Physical Sciences

Research areas and focus

  1. Microbubbles for the targeted destruction and delivery of drugs to biolfilms.
  2. Raman Spectroscopy & Microscopy of Bacteria and Biofilms.
  3. Computational Science and Engineering
    • Applied Computing in Biology, Medicine and Health
    • Artificial Intelligence
    • Distributed Systems and Services
    • Algorithms and Complexity

Facilities

  • Microbubble/ Nanobubble production & characterisation
  • Targeting for biofilms
  • Ultrasound based disruption technology
  • Microfluidics
  • Combined Raman & Confocal Fluorescence Microscope
  • Combined Fluorescence & AFM

Researchers

Steven Evans
Christopher Wood
Steven Freear (Engineering)
Jon Sandoe (Medicine)
Dr David Head

School of Design
Clothworkers Centre For Textile Materials Innovation for Healthcare

Research areas and focus

  1. Development of Novel Fibrous Materials for Healthcare
  2. Development of Medical Devices for Healthcare Applications
  3. Engineering of Surface and Bulk Properties of Fibrous Materials

Facilities

  • Nanofibre and Conventional Spinning of Fibres and Biomaterials
  • 3D Weaving Innovation Centre for Structural Materials in Healthcare Applications
  • Nonwovens Centre for Innovative Materials
  • Knitting Technology
  • Digital Printing for Materials and Ink Development
  • Colour Imaging and Communication Facilities
  • Materials Testing Lab
  • Chemical Synthesis Lab

Researchers

Chris Carr
Steve Russell
Giuseppe Tronci

Department Link

School of Design