b'UNIVERSITY/PROJECT TITLE PROJECT SUMMARY RESEARCHCOLLABORATOR/SINSTITUTIONEvaluating anIn the food industry, increased resistanceUniversity ofFourth Stateinnovative plasmaof biofilm-forming bacteria such as ListeriaSurrey Medicine Ltd(fourth state ofhas led to a need for new approaches for matter) decontamination of food and food processing technology forsurfaces. This project will evaluate an innovative prevention andplasma (fourth state of matter) technology for management ofbiofilm prevention and management on food and biofilms in thehard surfaces.food industryA novel laboratoryOrganisation of bacteria as communities calledUniversity ofNeem Biotech biofilm model tobiofilms in wounds delays healing.In the UK,Sheffield and Welsh Wound accelerate thecurrently one million patients live with theInnovation Centrecommercialisationphysical and emotional discomfort caused by of anti-biofilmnon-healing wounds. This project will help bring products for theto the clinic a unique, revolutionary cure that will benefit of patientsaccelerate wound healing by removing biofilms.with chronic woundsFacile fabricationTitanium dental implants to replace damaged orUniversity of theOsteoCareof a disruptivemissing teeth can sometimes get infected. WeWest of England titaniumhave taken inspiration from how edible mussels(UWE), Bristoltechnology usingattach to rocks, jetties etc. by applying a thin film a polydopamineof the adhesive used by mussels on titanium. The capturingfilm in turn can hook suitable agents to minimise platform infection.BiofilmThe ability of antibiotics to penetrate the biofilmUniversity ofPerfectus Biomed Ltdfluorescentmatrix is key to their clinical success, but hard toWarwickantibiotics assay measure.We will assess a novel method to detect how well antibiotics penetrate biofilms in chronic lung infections. We will use fluorescently-tagged antibiotics within clinically relevant and UKAS accredited biofilm methods.Development ofMarine fouling biofilm contributes to thousandsUniversity ofInternational Paint synthetic biofilmof tonnes excess fuel usage in the shippingSouthampton Ltd (AkzoNobel)for calibratingindustry. We will develop a test system that can the effect ofmore accurately predict how a coating may reduce coatings onbiofilm viscoelastic drag to aid in the design and reducing marineapplication of better, environmentally friendly viscoelastic drag coatings for marine vessels.QuorumClean This project aims to develop a novel marinePlymouth MarineUnilever R&D Port antifouling technology that outperformsLaboratory Sunlightconventional approaches, but with a reduced environmental impact. The approach works by disrupting cell-to-cell communication between marine microbes. Potential applications of the technology are diverse and include protection of ship hulls, marine sensors, desalination membranes and aquaculture infrastructure.48'