b'UNIVERSITY/PROJECT TITLE PROJECT SUMMARY RESEARCHCOLLABORATOR/SINSTITUTIONImpact of ozoneListeria monocytogenes is a food-borne bacteriumJames HuttonAnacail Ltdapplication on Listeriathat can cause serious and sometimes fatal diseaseInstitutemonocytogenes biofilmsin humans. Food factory drains can harbour Listeria on drain covers underbiofilms, hence the need for thorough cleaning food processingtechniques. This project will test the extent of relevant conditions reduction of Listeria by Anacails high-dose ozone in factory-relevant conditions on drain covers.Bacterial networking;Bacteria in wastewater treatment works canUniversity ofVeolia UKwhy its not alwaysform complex network-like structures that can beEdinburghbeneficial to builddetrimental to the treatment process. In this Proof bridges and makeof Concept project, we will perform experiments connections and computer simulations to understand the mechanisms by which these structures form. The insight gained will help us inhibit their occurrence. Developing passivePathogenic yeasts can grow as biofilms on materialsUniversitySmiths Medical RFID technology toused to make medical implants, this represents aofKent International Ltdmonitor Candidasignificant infection risk to vulnerable patients. We albicans biofilm growthwill develop methods to detect biofilm growth on on medical devices medical devices within patients and in real-time using radio-frequency identification (RFID) technology, this will help improve diagnosis and treatment.Label-free multimodalBiofilms are groups of bacteria that are very difficultUniversity ofM Squared imaging platform forto detect. Were combining powerful chemical andSouthampton Life Ltd and detection of biofilms molecular technologies in a volumetric imagingUniversity platform to analyse biofilms quickly through theirHospital unique characteristics. This will help in diagnosis,Southamptontreatment avoiding anti-microbial resistance and remove or promote biofilms in health and industrial applications.Rapid screeningUrological devices are widely used to treat kidneyUniversity ofPublic Health platform for shortlistingstones, tumours, and incontinence. However,Southampton England coatings againstthey significantly suffer from biofilm formation,and Center infection causing severe side effects. Here, we will developfor Biofilm the first microfluidic platform for rapid screening ofEngineering coatings that prevents/addresses biofilms, enabling(CBE) Montana development of safer urological devices and withState Universitywider potential applications.Advanced biofilmIn this proposal we will develop an innovativeUniversity ofPerlemax Ltdremoval mediated bymultidisciplinary approach to identify key componentsSheffieldtargeted microbubblesof bacterial physicochemical characteristics of both generated by fluidicstatic and dynamic biofilms, which will provide a oscillation biomarker for biofilm stability and a target for biofilm removal using our patented novel technology of microbubbles generated by fluidic oscillation.Automated in situThis project aims to adopt a uniquely designedNewcastleInternational detection and monitoringautomated in situ testing rig to detect and monitorUniversity Paint Ltd of marine biofilmmarine biofilm erosion and study their mechanical(AkzoNobel) and erosion and mechanicalproperties. This would address the influence ofUniversity of properties via custombiofilms on the drag on marine vessels with the aimSouthamptonoptical coherenceof improving development of anti-fouling coatings to tomography (OCT) reduce fuel costs.52'