b'Proof of Concept 2AWARDED JULY 2019UNIVERSITY/PROJECT TITLE PROJECT SUMMARY RESEARCHCOLLABORATOR/SINSTITUTIONAlgae-poweredWe have shown that algal biofilms can generate smallUniversity ofArm Ltdmicroprocessors amounts of electrical power, which can be used to runCambridgesmall electronic devices. We aim to prove the concept that we can use a conveniently sized algal biofilm to power a microprocessor - a computer powered by algae.Development ofImplanted medical devices improve quality of life forNottinghamESP Technology the first ESPRIT- millions of people. However, a major complication ofTrentLtd and Harman AM antimicrobialthese devices is biofilm infection. Current implantableUniversity Technology Ltdself-sealing vasculardevices offer little resistance to biofilm formation. This access graft project will develop novel anti-biofilm medical device coatings to reduce the incidence and severity of biofilm infection. Enhanced biofilmBiofilms growing on historic buildings and artefactsUniversity ofHistoric England detection methodscan cause serious damage, with critical implicationsPortsmouth and Isle of Wight and the use offor their conservation. This collaboration with HistoricHeritage Service, UVC light in theirEngland will investigate novel on-site biofilm detectionIsle of Wight remediation andmethods and the use of UV-C as a cost-effective,Councilcontrol on historicreliable and non-destructive remediation tool for many buildings andendangered historic buildings.artefactse-Biofuels frome-biosynthetic fuels from alternative resources ratherLoughboroughShell Research LtdCO2 conversionthan petrochemicals are essential to transition to aUniversity and using microbiallow carbon future with reduced green gas emission toNewcastleelectrosynthesis tackle climate change, whilst meeting energy security.UniversityMicrobial electrosynthesis is a promising way using microorganisms and renewable energy to convert CO2 to fuels and chemicals.Electrical sensorsQuantifying biofilms in drinking water pipe networksUniversity ofEnvironmental for environmentalcurrently relies on removal of samples for laboratorySheffield Monitoring & civil engineers: inanalysis, which suffers from limits-of-detection, and isSolutions Ltd situ online biofilmintrusive, costly and time-consuming. We propose a newand Water characterisation electrical sensor to detect and quantify biofilms in situIndustry Process and in real-time, validating against current state-of-the- Automation & art laboratory measurements. ControlGas plasma for theOsteomyelitis is a biofilm infection of bone whichUniversity ofAdtecprevention andis difficult to treat. This project will develop a novelHullmanagement oflaboratory testing model to evaluate and optimise a osteomyelitis biofilms plasma treatment for osteomyelitis biofilm infections. Examining theAntibiotic-resistant bacteria and fungi pose a significantUniversity ofDestiny Pharma potential ofthreat in ophthalmic e.g. microbial keratitis, resulting inSheffield plcpharmaceutical agentsvision impairment and blindness particularly in lower (XF-drugs) to preventto middle income countries. The purpose of this study and proactivelyis to examine the effectiveness of novel antimicrobial-manage bacterial anddrugs, against clinically relevant bacterial and fungal fungal infections in aspecies in a model system.dynamic ex vivo ocular model system51'