b'UNIVERSITY/PROJECT TITLE PROJECT SUMMARY RESEARCHCOLLABORATOR/SINSTITUTIONOrgano-metallicThis study will explore the application of antibiofilmSheffield5D Health HIPIMS-coatednanoscale organo-metallic coatings to advancedHallamProtection Group antibiofilm advancedwoundcare dressing substrates using the lowUniversity Ltdwound dressings environmental impact processes of HIPIMS and aqueous application. This new class of wound dressings would have the potential to greatly enhance patient outcomes and significantly reduce healthcare costs.The standardMethods and materials to support the standardisationUniversity ofLGC Ltdbiofilm: a referenceof biofilm analysis which are lacking in all industrialSouthamptonmeasurementsectors where biofilms are important. This project system to supportaims to address this need by developing methods routine manipulation,to produce and characterise reference materials to innovation andvalidate biofilm analysis and technical approaches used application in various industrial sectors. Novel approach toOsteomyelitis is a bone disease mostly caused byUniversity ofCeramisys Ltd and treat osteomyelitisbiofilms in bone injuries or surgical sites sometimesNottingham Upperton Pharma biofilms combiningleading to bone removal. We will use a novel approachSolutionsinnovative dualto treat osteomyelitis biofilms combining innovative therapy and slow drugdual therapy targeting bacterial communication release mechanisms with antibiotics and slow drug release.Evaluating theThere is an increasing demand for natural supplementsUniversity ofPukka Herbs Ltdantimicrobial activityin the consumer healthcare and wellbeing market,Southamptonof herbal infusions:with more people taking a holistic approach to self-implications forcare. Herbal products are widely used in traditional consumer healthcaremedicines. This study will investigate the antimicrobial and well-being effects of Pukka herb products and establish optimal effective combinations. Antibiofilm touchThis proposal explores developing plastics on whichUniversity of5D Health point plastics microorganisms will not grow, either in planktonic orWarwick Protection Group biofilm state. The resultant plastics, processable byLtdtypical mass production techniques will enable a huge range of end products across plastics surfaces and touch points.Development ofThere is a current need for realistic efficacy assays forUniversity ofBear Valley an in vitro humanscreening hand disinfectant products that are simple,Edinburgh Ventures and skin biofilm modelaffordable and high-throughput. In this project, weAqualution for testing activewill partner with Bear Valley Ventures and AqualutionSystems Limitedingredients for handto develop a human skin biofilm model that can be hygiene used for high-throughput testing of skin disinfection formulations. To incorporate aThe general aim of this proof of concept study isUniversity ofUnilever and quorum sensingto develop and evaluate a pioneering topical skinGlasgow Penrhos Bioblocker (lactams) intotreatment to be used as a new smart technology topical treatments tofor the effective management of complex biofilm control mixed biofilmsinfections. This has the potential as an alternative on keratinaceousfor anti-microbial resistant infections and reduce infections healthcare costs.57'