b'UNIVERSITY/PROJECT TITLE PROJECT SUMMARY RESEARCHCOLLABORATOR/SINSTITUTIONTo incorporate aThe general aim of this Proof of Concept of study is toUniversity of5D Health quorum sensingdevelop and evaluate a pioneering wound dressing toLiverpool Protection Group blocker (lactams)be used as a new, smart technology for the effectiveLtd, Penrhos Bio into wound dressingmanagement of biofilms in wounds, which has theand Unileverplatforms to controlpotential to greatly enhance patient outcomes and biofilms reduce healthcare costs.Biofilm disruptionPotential methods to treat wound infections includeUniversity ofIo-Cyte Ltd and activity of absorbentusing absorbent dressings containing alginate forNottingham University of sustained actionantimicrobial sustained-release. Alginate-IodineSouthamptonalginate and iodinecombinations have shown considerable promise combined woundagainst single-species biofilms. Here we evaluate dressings disruption of persistent polymicrobial inter-kingdom and single-species wound biofilms utilising different formulations of absorbent sustained-action alginate/iodine dressings in abiotic and biotic biofilm models.Novel hybrid biofilmNutrient removal represents a significant challengeUniversity ofPlantwork Systems technology to removeto the water industry, housing development and localSouthampton Ltdnutrients fromeconomy, particularly in the Solent region. This project wastewater aims to demonstrate a hybrid biofilm system in a full-scale prototype plant achieving total nitrogen and total phosphorus concentrations below 5 and 0.5 mg/L, respectively, in treated effluent. Dry surface biofilms,Surfaces within a healthcare environment can beUniversity ofGenesis understandingcoated with potentially infectious organisms whichHuddersfield Biosciences their formationsurvive by forming a dry biofilm. The project seeks to and developmentfurther understand the form and function of these of a test model forbiofilms whilst generating a test method to assess preventative surfacepreventative surface cleansers.cleansers55'